0

CMHC PULSE

Cardio Metabolic Health Congress – Official Blog

Bariatric Surgery Appears to Cure Half of Patients with T2DM for at Least 5 Years

In a study of obese patients with type 2 diabetes, bariatric surgery was found to be more effective than medical treatment in the long-term control of the disease (for at least 5 years). The study consisted of 60 patients randomized to either medical treatment or surgery (Roux-en-Y gastric bypass or biliopancreatic diversion). The primary endpoint was the rate of diabetes remission at 2 years (defined as HbA1c of 6.5% or less and a fasting glucose concentration of 5.6 mmol/L or less) without active pharmacologic treatment for 1 year. Patients were followed up for 5 years. Among 38 patients who underwent surgery, 19 (50%) maintained diabetes remission at 5 years compared with none of the 15 medically treated patients. The study authors advise continued monitoring of glycemic control because of a potential relapse for hyperglycemia.

Read the complete study here in The Lancet. To learn more from one of the study authors, Dr. Francesco Rubino, be sure to attend the 10th Annual CMHC where he will co-present “Long-Term and Metabolic Effects of Bariatric Surgery” on Friday, October 23, from 3:25 – 4:05 pm with Dr. Lee M. Kaplan.

Elevated Blood Pressure Increases Risk of Type 2 Diabetes

Results of a recent study published in the Journal of the American College of Cardiology are lending weight to the widely believed hypothesis that hypertension is an independent risk factor for type 2 diabetes. The study, an analysis of electronic health records and a meta-analysis, consisted of 4.1 million adults without diabetes and cardiovascular disease. The objective was to evaluate the association between usual blood pressure and risk of diabetes.

Each 20 mmHg increase in systolic blood pressure and 10 mmHg increase in diastolic blood pressure was associated with a 58% and a 52% higher risk of new-onset diabetes. The strength of that association per 20 mmHg higher SBP decreased with age and increasing body mass index. According to the study authors, “Elevated blood pressure is associated with chronic inflammation and endothelial dysfunction, both of which appear to be mediators of diabetes risk. There is, therefore, a biological rationale to suspect that elevated blood pressure may cause new-onset diabetes.” Read more